Skin Whitening and Brightening

Our skin is constantly exposed to a variety of stressors that can dull its natural radiance and cause discoloration. Factors such as UV exposure, pollution, hormonal changes, and aging can lead to the overproduction of melanin, resulting in dark spots, uneven skin tone, and a lackluster complexion.

Both extrinsic factors (like environmental pollutants) and intrinsic factors (such as genetic predispositions) contribute to these changes. These stressors compromise skin integrity by affecting the melanocytes, the cells responsible for pigment production. This can lead to hyperpigmentation and an overall dull appearance. However, these effects can be mitigated by targeting specific molecular pathways with specialized skin care products. By incorporating ingredients that inhibit melanin production and promote cell turnover, skin whitening and brightening products can help achieve a more even and luminous complexion.

Cosmetic Products

Organic Soaps

Powders

Serums

Face mask

Biomarker Testing List:

BiomarkerScientific Pathway DetailsUsed to Prove Claims
(MMPs)They play critical roles in various physiological and pathological processes including tissue remodeling, wound healing, angiogenesis, and metastasis. Protects against collagen breakdown."
(Ascorbic Acid)Ascorbic acid is a vital water-soluble vitamin functioning as an antioxidant and a cofactor in various enzymatic reactions. It is essential for collagen synthesis, immune function, and neurotransmitter production.Brightens skin tone
NiacinamideNiacinamide is a form of Vitamin B3 essential for the synthesis of NAD+ (Nicotinamide adenine dinucleotide) and NADP+, coenzymes involved in numerous metabolic processes including energy production, DNA repair, and cell signaling.Improves skin texture and tone
 I collagenType I collagen is the most abundant collagen type in the human body, providing structural support to various tissues including skin.Boosts skin firmness and elasticity
 type III collagenPlays a critical role during wound healing, being one of the first collagens deposited in the granulation tissue and later replaced by Type I collagen.Supports youthful skin structure
 IL-6, and IL-8.IL-6 is a multifunctional cytokine involved in immune responses, inflammation.Reduces inflammation/Soothes inflamed skin

Scientific Driven with our Technology:

Using our expertise in immunology and cell culture, we develop immunoassays based on ELISA principle. Using cutting edge tools like 3D tissues (some of which are OECD approved for skin / cornea irritation), we bring the human experimentation into the labs. Curating a list of research publications, we have developed a platform to test products for their biomarkers mimicking the human model to generate data to back our label claims.    

Read our Blog on Cosmetic Product Claims and other Product Claims (natural / herbal / naturopathy etc)

Reference Research Publications

 https://doi.org/10.1111/jocd.13741

Related Services

Cell Viability and Cytotoxicity Testing

Ensures that the ingredients do not harm skin cells while exerting their brightening effects.

Tyrosinase Inhibition Assay

Assesses the product’s ability to inhibit tyrosinase, a key enzyme involved in melanin production. Reduced tyrosinase activity can lead to a decrease in melanin synthesis, contributing to a lighter skin tone.

Melanin Content Assay

Measures the effect of the product on melanin production in cultured melanocytes (skin cells responsible for pigmentation). A reduction in melanin levels indicates potential skin whitening effects.

Skin Color Measurement (Reflectance Spectroscop)

Measures changes in skin color or tone in the RHP model.

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