Dark Circle Reduction

The “No Dark Circle Reduction” claim on skincare products refers to the product’s efficacy in reducing the appearance of dark circles under the eyes. This claim suggests that the product contains ingredients specifically formulated to target hyperpigmentation, improve blood circulation, and hydrate the delicate skin around the eyes. Typically, such products may include brightening agents, peptides, and other nourishing components that work together to lighten dark circles and restore a more youthful, refreshed appearance. Consumers seeking solutions for tired, dull-looking eyes often look for this claim as a sign that the product can effectively address their concerns and deliver visible results.

Roll-On Treatments

Natural supplements

Creams

Serums

Eye mask

Biomarker Testing List:

BiomarkerScientific Pathway DetailsUsed to Prove Claims
Melanin levelThe amount of melanin pigment in the skin, determining skin color and providing protection against UV radiation.Skin lightening, brightening, even skin tone
(IL-6)A cytokine that signals through the JAK/STAT3 pathway, mediating inflammation, acute-phase reactions, and immune responses.Anti-inflammatory, soothing, anti-redness
Collagen Type IThe most abundant collagen in the body, forming strong fibrils that provide tensile strength to skin, bones, tendons, and other connective tissues.Anti-aging, wrinkle reduction, skin firming
(MMPs)Zinc-dependent proteases that degrade extracellular matrix components, involved in tissue remodeling, inflammation, and cancer metastasis.Anti-aging, skin protection
Natural Moisturizing Factor (NMF)Hydration, moisturizing, improving skin barrier function, and preventing dryness.

Scientific Driven with our Technology:

Using our expertise in immunology and cell culture, we develop immunoassays based on ELISA principle. Using cutting edge tools like 3D tissues (some of which are OECD approved for skin / cornea irritation), we bring the human experimentation into the labs. Curating a list of research publications, we have developed a platform to test products for their biomarkers mimicking the human model to generate data to back our label claims.   

Read our Blog on Cosmetic Product Claims and other Product Claims (natural / herbal / naturopathy etc).

Reference Research Publications:

Clinical evidence of the efficacy and safety of a new multi-peptide anti-aging topical eye serum

Journal of cosmetic dermatology

Fengzhu Li MDHaowei Chen PhDDongxiao Chen MDBingjie Zhang MDQingying Shi PhDXihong He PhDHuabing Zhao PhDFang Wang PhD

published: 19 June 2023

https://doi.org/10.1111/jocd.15849

Periorbital Hyperpigmentation—Dark Circles under the Eyes; Treatment Suggestions and Combining Procedures

Alberto Goldman 1 , Mohamad Goldust 2 and Uwe Wollina 3,

Published: 26 March 2021

https://doi.org/10.3390/cosmetics8020026

Biopigments of Microbial Origin and Their Application in the Cosmetic Industry

Manal Jameel Kiki

Published: 10 March 2023

https://doi.org/10.3390/cosmetics10020047

Related Services

In-Vitro Melanin Production Assay

Measures the product's effect on melanin levels in ocular tissue models to evaluate its ability to reduce dark circles.

In-Vitro Circulation Improvement Testing

Assesses the product’s impact on microcirculation and blood flow in eye area models to help reduce the appearance of dark circles.

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