No Tears
The “No Tear Drops” claim on personal care products, particularly baby shampoos and cleansers, signifies a formulation designed to be exceptionally gentle on the eyes, reducing the likelihood of irritation or stinging if the product accidentally comes into contact with them. This claim is backed by rigorous testing to ensure that the product meets safety standards, providing peace of mind to consumers, especially parents, who prioritize the comfort and well-being of their children. By emphasizing mildness, the “No Tear Drops” label differentiates the product in a competitive market, appealing to those seeking gentle, safe options for sensitive skin.
Eye drops
Eye Makeup Removers
Eye creams
Mascara
Contact lens
Eye Mask
Biomarker Testing List:
| Biomarker | Scientific Pathway Details | Used to Prove Claims |
|---|---|---|
| Cortisol levels | A measure of the stress hormone cortisol, which regulates various physiological processes including metabolism, immune response, and inflammation. | Anti-stress, soothing, anti-inflammatory |
| E2 ( PGE 2) | A lipid mediator produced from arachidonic acid, involved in inflammation, fever, and pain modulation. | Anti-inflammatory, redness reduction |
| IL-6, TNF-alpha | A cytokine that signals through the JAK/STAT3 pathway, mediating inflammation, acute-phase reactions, and immune responses. | skin calming, anti-aging, |
| MMP-9 | An enzyme that degrades type IV and V collagens, facilitating tissue remodeling and playing a role in inflammation. | promoting skin repair. |
| IL-8 | A chemokine that attracts neutrophils to sites of infection or inflammation, playing a key role in the inflammatory response. | reducing skin redness and irritation. |
| IL-17A | A pro-inflammatory cytokine produced by Th17 cells, involved in the defense against extracellular pathogens and the pathogenesis of autoimmune diseases. | calming irritated or inflamed skin. |
Scientific Driven with our Technology:
Using our expertise in immunology and cell culture, we develop immunoassays based on ELISA principle. Using cutting edge tools like 3D tissues (some of which are OECD approved for skin / cornea irritation), we bring the human experimentation into the labs. Curating a list of research publications, we have developed a platform to test products for their biomarkers mimicking the human model to generate data to back our label claims.
Read our Blog on Cosmetic Product Claims and other Product Claims (natural / herbal / naturopathy etc).
Reference Research Publications:
TFOS Lifestyle: Impact of cosmetics on the ocular surface
National library of medicine
David A. Sullivan, Alexandre X. da Costa, Ester Del Duca,Tracy Doll,Christina N. Grupcheva, Sihem Lazreg,Su-Hsun Liu, Selina R. McGee, Rachna Murthy,i Purvasha Narang,j Alison Ng,k Steven Nistico, Leslie O’Dell, Jonathan Roos,Joanne Shen,and Maria Markoulli
Published – 2023 Jul 29
Allergy and the eye
Journal of immunology
A Leonardi, L Motterle, and M Bortolotti
2008 Sep