Non-Irritating / Gentle
The “Non-Eye Irritant” claim on a product indicates that it has been formulated and tested to ensure that it does not cause irritation or discomfort if it comes into contact with the eyes. This claim is particularly important for products used near the eye area, such as cosmetics, skincare items, and shampoos, where accidental exposure is common. Through rigorous testing, often involving clinical evaluations by dermatologists and ophthalmologists, these products are verified to be gentle and safe, minimizing the risk of redness, stinging, or watering of the eyes. For consumers, the “Non-Eye Irritant” label provides reassurance that the product can be used safely without causing harm to this sensitive area.
Fake eyelashes
Contact lens
Eye drop
Shampoos
Eye cleansers
Biomarker Testing List:
| Biomarker | Scientific Pathway Details | Used to Prove Claims |
|---|---|---|
| 1 (IL-1) | Interleukin-1 (IL-1) binds to its receptor (IL-1R) on target cells, activating intracellular signaling pathways like NF-κB and MAPK, leading to the expression of pro-inflammatory cytokines and immune responses. | restore ocular surface health. |
| Ocular Surface Integrity | Ocular surface integrity is like the protective shield of the eye, ensuring its outermost layers—cornea, conjunctiva, and tear film—stay intact to guard against harm and keep vision clear. | reducing symptoms like dryness, irritation, or damage. |
| Cell Viability | Cell viability is the ability of cells to survive, function, and maintain integrity under specific conditions. | protecting eye health and preventing damage. |
Scientific Driven with our Technology:
Using our expertise in immunology and cell culture, we develop immunoassays based on ELISA principle. Using cutting edge tools like 3D tissues (some of which are OECD approved for skin / cornea irritation), we bring the human experimentation into the labs. Curating a list of research publications, we have developed a platform to test products for their biomarkers mimicking the human model to generate data to back our label claims.
Read our Blog on Cosmetic Product Claims and other Product Claims (natural / herbal / naturopathy etc).
Reference Research Publications:
Evaluation of the clinical efficacy and safety of an eye counter pad containing caffeine and vitamin K in emulsified Emu oil base
Fatemeh Ahmadraji, Mohammad Ali Shataleb
Accepted: 09.02.2013
10.4103/2277-9175.148292
https://journals.lww.com/adbm/_layouts/15/oaks.journals/downloadpdf.aspx?an=01679891-201504000-00010
Ocular Discomfort Responses after Short Periods of Contact Lens Wear
Journal of American of Optometry
Papas, Eric ; Tilia, Daniel ; McNally, John ; de la Jara, Percy Lazon
Three-tier testing approach for optimal ocular tolerance sunscreen
Mridvika Narda, David Ramos-Lopez, Greg Mun, Palmira Valderas-Martinez & Corinne Granger
07 May 2019