Anti-Oxidant
Antioxidant ingredients for skin and hair care products.
Oxidative stress is a key contributor to skin aging, affecting both the surface and deeper layers of the skin. Factors such as environmental pollution, sun exposure, stress, and fatigue generate free radicals, which damage skin cells. These free radicals attack cell organelles, like mitochondria, triggering an inflammatory response. As a result, essential proteins in the dermal structure are altered, and membrane lipids and DNA suffer damage.
This disruption in skin cell metabolism slows down regeneration and may impair it, leading to cell senescence and premature aging. The skin may lose its firmness, appear dull, develop wrinkles, and show pigmentation spots.
Cosmetic Products
Natural Foods
Natural Extract Oils
Vitamin C Serums
Resvaratrol Supplements
Biomarker Testing List:
Biomarker | Scientific Pathway Details | Used to Prove Claims |
---|---|---|
C (Ascorbic Acid) | Inside cells, Vitamin C acts as a potent antioxidant | skin brightening |
Vitamin E (Alpha-Tocopherol) | Vitamin E can be regenerated by Vitamin C, enhancing its antioxidant effects. | protection against UV damage. |
(GSH) | GSH acts as a major intracellular antioxidant. | detoxification, skin brightening |
(TAC) | TAC is a measure of the combined antioxidant capabilities of various antioxidants present in a biological sample | Overall antioxidant protection |
(CRP) | It is a marker of systemic inflammation produced in response to inflammatory cytokines. | protection against aging |
Scientific Driven with our Technology:
Using our expertise in immunology and cell culture, we develop immunoassays based on ELISA principle. Using cutting edge tools like 3D tissues (some of which are OECD approved for skin / cornea irritation), we bring the human experimentation into the labs. Curating a list of research publications, we have developed a platform to test products for their biomarkers mimicking the human model to generate data to back our label claims.
Read our Blog on Cosmetic Product Claims and other Product Claims (natural / herbal / naturopathy etc)
Reference Research Publications
Oxidative Stress and Antioxidants—A Critical Review on In Vitro Antioxidant Assays
MDPI journal
Raghavendhar R. Kotha, Fakir Shahidullah Tareq, Elif Yildiz, Devanand L. Luthria
Published: 1 December 2022
https://doi.org/10.3390/antiox11122388
Polyphenols as natural antioxidants in cosmetics applications
Journal of cosmetic dermatology
Débora Jackeline de Lima Cherubim MSc, Cleide Viviane Buzanello Martins PhD, Luciana Oliveira Fariña PhD, Rosemeire Aparecida da Silva de Lucca PhD
First published: 07 August 2019
Related Services
Cell-Based Antioxidant Assays
In-vitro assays using cell models to assess the protective effect of antioxidants against oxidative stress in living cells, simulating real-life conditions.
DPPH (2,2-Diphenyl-1-picrylhydrazyl) Assay
A common in-vitro method used to evaluate the free radical scavenging ability of antioxidants in a product by observing color changes in a solution.
Lipid Peroxidation Assay
This test evaluates the ability of antioxidants in products to prevent the oxidation of lipids, which is a common cause of skin aging.