Pigmentation Related
Radiant skin is often associated with good health, vitality, and youth. Achieving that “healthy glow” is a popular cosmetic goal for many users. However, factors such as a hectic lifestyle, pollution, stress, fatigue, cigarette smoke, and sun exposure can all contribute to a dull complexion. Aging also impacts skin radiance, as the skin tends to lose its glow over time, developing folds and wrinkles.
Skin texture is crucial in maintaining radiance. As we age, the skin’s microrelief deteriorates, causing it to reflect less light and gradually lose its brightness. Additionally, skin radiance is affected by pigmentation balance. When pigmentation becomes irregular, spots and blemishes can appear. This disruption is linked to keratinocytes and melanocytes, the main epidermal cells responsible for synthesizing melanin, the pigment that gives skin its color.
Cosmetic Products
Natural Foods
Serums
Creams
Vitamin E capsules
Biomarker Testing List:
| Biomarker | Scientific Pathway Details | Used to Prove Claims |
|---|---|---|
| (IL-6, IL-1β) | pro-inflammatory cytokines that play significant roles in the immune response, inflammation, and aging processes within the skin | Anti-inflammatory, soothing, treatment |
| Vitamin C Level | Refers to the concentration of ascorbic acid, a potent antioxidant that supports collagen synthesis and protects against oxidative stress. | Antioxidant protection, skin brightening |
| (CRP) | An acute-phase protein that increases in response to inflammation, used as a biomarker for systemic inflammation. | Anti-inflammatory, skin-calming |
| 8-OHdG | A biomarker for oxidative DNA damage, formed when reactive oxygen species attack guanine bases in DNA. | anti-aging, reducing oxidative stress |
| K16, K17 | A cytoskeletal protein expressed during skin injury and disease, involved in regulating cell proliferation and the inflammatory response. | skin barrier repair. |
Scientific Driven with our Technology:
Using our expertise in immunology and cell culture, we develop immunoassays based on ELISA principle. Using cutting edge tools like 3D tissues (some of which are OECD approved for skin / cornea irritation), we bring the human experimentation into the labs. Curating a list of research publications, we have developed a platform to test products for their biomarkers mimicking the human model to generate data to back our label claims.
Read our Blog on Cosmetic Product Claims and other Product Claims (natural / herbal / naturopathy etc)
Reference Research Publications:
Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial
Journal of cosmetic dermatology
Pattarawan Rattanawiwatpong MD, Rungsima Wanitphakdeedecha MD, MA, MSc, Akkarach Bumrungpert PhD, Mart Maiprasert MD
First published: 24 January 2020