Skin Whitening Panel

Our skin is constantly exposed to a variety of stressors that can dull its natural radiance and cause discoloration. Factors such as UV exposure, pollution, hormonal changes, and aging can lead to the overproduction of melanin, resulting in dark spots, uneven skin tone, and a lackluster complexion.

Both extrinsic factors (like environmental pollutants) and intrinsic factors (such as genetic predispositions) contribute to these changes. These stressors compromise skin integrity by affecting the melanocytes, the cells responsible for pigment production. This can lead to hyperpigmentation and an overall dull appearance. However, these effects can be mitigated by targeting specific molecular pathways with specialized skin care products. By incorporating ingredients that inhibit melanin production and promote cell turnover, skin whitening and brightening products can help achieve a more even and luminous complexion.

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Melatonin Inhibition
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Biomarker Testing List:

BiomarkerRemarks on the Biomarker
(MMPs)They play critical roles in various physiological and pathological processes including tissue remodeling, wound healing, angiogenesis, and metastasis.
(Ascorbic Acid)Ascorbic acid is a vital water-soluble vitamin functioning as an antioxidant and a cofactor in various enzymatic reactions. It is essential for collagen synthesis, immune function, and neurotransmitter production.
NiacinamideNiacinamide is a form of Vitamin B3 essential for the synthesis of NAD+ (Nicotinamide adenine dinucleotide) and NADP+, coenzymes involved in numerous metabolic processes including energy production, DNA repair, and cell signaling.
 I collagenType I collagen is the most abundant collagen type in the human body, providing structural support to various tissues including skin.
 type III collagenPlays a critical role during wound healing, being one of the first collagens deposited in the granulation tissue and later replaced by Type I collagen.

Reference Research Publications

  • A novel skin brightening topical technology

  • Skin brightening & whitening (MMPs), (Ascorbic Acid), (ROS), Niacinamide, I collagen,  type III collagen,  IL-6, and IL-8. 

  • A novel skin brightening topical technology

  • Journal of cosmetic dermatology

  • Zoe Diana Draelos MD, Isabel Diaz BA, Aaron Cohen PhD, Junhong Mao PhD, Thomas Boyd PhD

  • First published: 28 September 2020

  •   https://doi.org/10.1111/jocd.13741

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