Itch Relief

The “Itch Relief” claim on skincare products indicates that the formulation is specifically designed to alleviate itching and discomfort in the sensitive eye area. This claim is typically associated with products that contain soothing and anti-inflammatory ingredients to address irritation. Key components often include cucumber extract, which provides a cooling effect and reduces inflammation, and aloe vera, known for its hydrating and calming properties. Chamomile extract is also commonly used for its anti-inflammatory and soothing effects, which help to calm irritated skin. Additionally, hyaluronic acid helps to maintain hydration and create a barrier that protects the skin from further irritation. These ingredients work together to relieve itching and soothe the delicate skin around the eyes, providing comfort and reducing the discomfort associated with dryness, allergies, or environmental factors. By focusing on these soothing and hydrating elements, “Itch Relief Eye” products aim to provide immediate relief and support long-term eye area comfort.

Cream

Drops

Cooling gel

Hair mask

Biomarker Testing List:

BiomarkerScientific Pathway DetailsUsed to Prove Claims
E (IgE)An antibody that binds to allergens and triggers mast cell degranulation, leading to allergic reactions and inflammation.Anti-allergic, anti-inflammatory, and sensitive skin claims
IL-4A cytokine that promotes Th2 cell differentiation and IgE class switching in B cells, playing a key role in allergic responses.anti-allergic, and skin-soothing claims
IL-13A cytokine involved in allergic inflammation, it works with IL-4 to induce IgE production and promote mucus secretion.improving skin health in conditions like eczema.
TNF-αA pro-inflammatory cytokine that activates NF-κB, promoting inflammation and apoptosis in various tissues.treating acne
MMP-9An enzyme that degrades type IV and V collagens, facilitating tissue remodeling and playing a role in inflammation.improving skin barrier integrity

Scientific Driven with our Technology:

Using our expertise in immunology and cell culture, we develop immunoassays based on ELISA principle. Using cutting edge tools like 3D tissues (some of which are OECD approved for skin / cornea irritation), we bring the human experimentation into the labs. Curating a list of research publications, we have developed a platform to test products for their biomarkers mimicking the human model to generate data to back our label claims.   

Read our Blog on Cosmetic Product Claims and other Product Claims (natural / herbal / naturopathy etc).

Reference Research Publication

Alternative Methods for Eye and Skin Irritation Tests: An Overview

Journal of Pharmaceutical Sciences

M.P. Vinardell, M. Mitjans

Accepted 16 November 2006

https://doi.org/10.1002/jps.21088

Establishment of a new in vitro test method for evaluation of eye irritancy using a reconstructed human corneal epithelial model, LabCyte CORNEA-MODEL

Toxicology in Vitro

Masakazu Katoh, Fumiyasu Hamajima, Takahiro Ogasawara, Ken-ichiro Hata

Accepted 22 August 2013

https://doi.org/10.1016/j.tiv.2013.08.008

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