Eye Care Cosmetics, Contact Lenses, Colored Lenses, Mascaras Claim Panel
The eye region is sensitive and thus needs products that are equally safe and aesthetically enhancing. Eye cosmetics like mascaras, eyeliners, and eyeshadows enhance look but should pass stringent dermatological and ophthalmological tests to o avoid irritating, allergy, or damaging tear film stability. Main testing areas are skin and eye irritation, microbial contamination, and long-term compatibility with sensitive periorbital tissues.Some colored or clear contact lenses have functional or cosmetic advantages. Whereas clear lenses only correct vision, colored ones enhance an individual’s appearance by changing the color of the eye. They also need to comply with strict biocompatibility tests for issues such as dry eye, corneal abrasion, or infections. The assessments focus on their oxygen permeability, wettability, and microbial resistance. In colored lenses, non-toxic pigments have been investigated to ensure they do not in any manner interfere with lenses proper functionality or eye health. Safety also must address possible interactions between lens and eye cosmetics, thus ensuring the compatibility of the products to be used by lens wearers.The test utilizes several advanced techniques, numerous in-vitro reconstructed human cornea models, irritation assays (HET-CAM), and in-vivo tear film evaluation. The inclusion of functionality, safety, and aesthetic in these tests gives support to the development of groundbreaking safe eye cosmetics and contact lenses that further ensure the consumer’s wellbeing.
Test Menu |
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Acne / Spot Reduction Efficacy Test |
Acne And Hydration Efficacy |
Acne Free And Spot Removal |
Acne Free Efficacy |
Acne Removing Efficacy |
Acne Scars Test |
Anti-Acne / Oiliness |
Dead Skin Cell And Acne Free Efficacy |
Dead Skin Cell Removal Efficacy |
Dead Skin Cells And Brightining |
Exfoliation Test |
Serum
Pimple Patch
Powder
Cream
Face Mask
Face Gel
Biomarker Testing List:
Biomarker | Remarks on the Biomarker |
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Oxidative Stress Marker (Malondialdehyde [MDA]) | Oxidative stress worsens acne; lower levels show antioxidant activity, reducing inflammation. |
Sebum Production | Excessive sebum contributes to acne; reduction in sebum levels helps reduce clogged pores. |
Matrix Metalloproteinase (MMP-9) | Degrades skin tissue in inflamed areas; lower MMP-9 levels prevent acne scarring. |
Inflammatory Cytokine (Interleukin-8 [IL-8]) | Attracts immune cells to infection sites; reduced IL-8 levels indicate reduced inflammatory response. |
Cutibacterium acnes | Acne-causing bacteria; decreased bacterial load shows antibacterial effectiveness of the product. |
Pro-inflammatory Cytokine Interleukin-1 alpha (IL-1a) | Inflammatory cytokine elevated in acne; reduction indicates anti-inflammatory effects on the skin. |
Skin pH | An altered pH encourages bacterial growth; balanced skin pH supports healthier, acne-free skin. |
Transforming Growth Factor beta1 | Promotes scar formation; reduced TGF-β1 helps in healing acne without scarring. |
Keratin 5 | Keratin 5 is a structural protein found in the basal cells of the epidermis, playing a crucial role in maintaining the integrity and strength of the skin, particularly in areas subject to mechanical stress. |
Keratin 14 | crucial for maintaining skin cell integrity and providing mechanical strength to the skin, particularly in the epidermal cells of the skin and mucous membranes. |
Propionibacterium acnes | This bacteria contributes to acne inflammation; a lower count indicates reduced bacterial activity. |
Sebum Production | Sebum production refers to the secretion of oily substances by sebaceous glands, which helps lubricate and protect the skin but can contribute to acne when overproduced. |
Leukocytic Pyrogen Pro-Inflammatory Cytokine Interleukin-1 beta (IL-1b) | Interleukin-1 beta (IL-1β) is a pro-inflammatory cytokine that acts as a leukocytic pyrogen, triggering fever and promoting inflammation during immune responses. |
Sebum Production Levels | Excessive sebum contributes to acne; reduction indicates better oil balance and fewer breakouts. |
Propionibacterium acnes (P. acnes) Count | This bacteria contributes to acne inflammation; a lower count indicates reduced bacterial activity. |
Inflammatory Cytokine (Interleukin-1 [IL-1]) | Elevated levels indicate skin inflammation; reduction reflects improved skin health and reduced acne. |
Inflammatory Cytokine (Interleukin-8 [IL-8]) | A pro-inflammatory cytokine that plays a pivotal role in immune response, fever induction, and the activation of other inflammatory mediators. |
A pro-inflammatory cytokine that attracts and activates neutrophils, contributing to inflammation and immune defense. | |
Keratinocyte Hyperproliferation Markers | Increased keratinocyte activity can lead to clogged pores; lower levels suggest reduced pore blockage. |
Reference Research Publications:
https://doi.org/10.1016/j.tox.2007.05.005