Melanin Production Claim

Melanin is a pigment synthesized by melanocytes in the epidermis, primarily in response to ultraviolet (UV) radiation. The process of melanin production, known as melanogenesis, is initiated when UV exposure activates the melanocortin-1 receptor (MC1R) on melanocytes, triggering the conversion of tyrosine into melanin through the enzyme tyrosinase. This pigment acts as a natural defense mechanism by absorbing UV radiation, thereby reducing DNA damage, oxidative stress, and inflammation, which helps protect against skin cancer and photoaging. There are two main types of melanin: eumelanin, which provides brown to black pigmentation and offers stronger UV protection, and pheomelanin, responsible for yellow to red hues, which is less effective in UV protection. Melanin production also varies with genetic factors, skin type, and hormonal influences, contributing to the diversity in skin color and its varying ability to cope with UV exposure.

Test Menu
Acne / Spot Reduction Efficacy Test
Acne And Hydration Efficacy
Acne Free And Spot Removal
Acne Free Efficacy
Acne Removing Efficacy
Acne Scars Test
Anti-Acne / Oiliness
Dead Skin Cell And Acne Free Efficacy
Dead Skin Cell Removal Efficacy
Dead Skin Cells And Brightining
Exfoliation Test
serum

Serum

oil

Oil

capsule

Supplements

hand-cream

Cream

face-cream

Gel

Biomarker Testing List:

BiomarkerRemarks on the Biomarker
Melanocyte-Stimulating Hormone Stimulates melanocytes to produce melanin; elevated MSH levels suggest increased melanin synthesis
Melanin Content in Skin Cells (via Spectrophotometry)Measures melanin levels directly in skin samples, providing a clear indicator of pigmentation.
Glutathione Peroxidase (GPx)Converts hydrogen peroxide into water, another key marker of antioxidant activity.
Gene Expression of MITF, TYR, TYRP1, and TYRP2Genes involved in melanin synthesis, where upregulated expression indicates increased melanin production.
Tyrosinase ActivityTyrosinase is the key enzyme in melanin synthesis. Increased activity reflects higher melanin production.
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