SkinEthicTM RHPE / Reconstructed Human Pigmented Epidermis

Description:

The SkinEthicTM RHPE model is composed of normal human keratinocytes cultivated in the presence of melanocytes of phototype II, IV or VI, localized in the basal layer. The different tanning degrees of these constructs correspond macroscopically to 3 different phototypes of human skin.

Specific markers:

  • Melanocytes localized in the basal cell layer interspersed with basal cell keratinocytes.
  • Melanin distribution in the basal layer
  • Ki 67

in vitro

Applications:

  • Pigmentation
  • Depigmentation
  • Omics
  • UV Exposure
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